Intrinsic calcium sensitivity of tubulin polymerization. The contributions of temperature, tubulin concentration, and associated proteins.
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Intrinsic calcium sensitivity of tubulin polymerization. The contributions of temperature, tubulin concentration, and associated proteins.
The calcium concentration required to inhibit tubulin polymerization by 50% (Ca2+ sensitivity) extends from the micromolar to the millimolar range and is a function of a number of factors that include 1) a steep, inverse dependence on tubulin concentration: two-cycle tubulin has lower Ca2+ sensitivity than pure tubulin (prepared by a novel method described under "Appendix"); 2) temperature: Ca2...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1981
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)68580-7